A diacidic motif determines unconventional secretion of wild-type and ALS-linked mutant SOD1

The nutrient starvation-specific unconventional secretion of Acb1 in Saccharomyces cerevisiae requires ESCRT-I, -II, and -III and Grh1. In this study, we report that another signal sequence lacking cytoplasmic protein, superoxide dismutase 1 (SOD1), and its mutant form linked to amyotrophic lateral...

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Vydáno v:J Cell Biol
Hlavní autoři: Cruz-Garcia, David, Brouwers, Nathalie, Duran, Juan M., Mora, Gabriel, Curwin, Amy J., Malhotra, Vivek
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2017
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584182/
https://ncbi.nlm.nih.gov/pubmed/28794127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201704056
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