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Kaposi’s sarcoma–associated herpesvirus stably clusters its genomes across generations to maintain itself extrachromosomally

Genetic elements that replicate extrachromosomally are rare in mammals; however, several human tumor viruses, including the papillomaviruses and the gammaherpesviruses, maintain their plasmid genomes by tethering them to cellular chromosomes. We have uncovered an unprecedented mechanism of viral rep...

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Библиографические подробности
Опубликовано в: :J Cell Biol
Главные авторы: Chiu, Ya-Fang, Sugden, Arthur U., Fox, Kathryn, Hayes, Mitchell, Sugden, Bill
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584176/
https://ncbi.nlm.nih.gov/pubmed/28696226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201702013
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