MGMT and CALCA promoter methylation are associated with poor prognosis in testicular germ cell tumor patients

Testicular germ cell tumors (TGCT) represent the second main cause of cancer-related death in young men. Despite high cure rates, refractory disease results in poor prognosis. Epigenetic reprogramming occurs during the development of seminomas and non-seminomas. Understanding the molecular and genet...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Martinelli, Camila Maria da Silva, Lengert, André van Helvoort, Cárcano, Flavio Mavignier, Silva, Eduardo Caetano Albino, Brait, Mariana, Lopes, Luiz Fernando, Vidal, Daniel Onofre
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584175/
https://ncbi.nlm.nih.gov/pubmed/28881587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11167
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