Contribution of the clathrin adaptor AP-1 subunit µ1 to acidic cluster protein sorting

Acidic clusters act as sorting signals for packaging cargo into clathrin-coated vesicles (CCVs), and also facilitate down-regulation of MHC-I by HIV-1 Nef. To find acidic cluster sorting machinery, we performed a gene-trap screen and identified the medium subunit (µ1) of the clathrin adaptor AP-1 as...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Navarro Negredo, Paloma, Edgar, James R., Wrobel, Antoni G., Zaccai, Nathan R., Antrobus, Robin, Owen, David J., Robinson, Margaret S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584140/
https://ncbi.nlm.nih.gov/pubmed/28743825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201602058
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