Global Metabolomics Reveals the Metabolic Dysfunction in Ox-LDL Induced Macrophage-Derived Foam Cells

Atherosclerosis (AS) is a chronic disorder of large arteries that is a major risk factors of high morbidity and mortality. Oxidative modification LDL is one of the important contributors to atherogenesis. Macrophages take up ox-LDL and convert into foam cells, which is the hallmark of AS. To advance...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Xu, Wenjuan, Wei, Ziyi, Dong, Jiaojiao, Duan, Feipeng, Chen, Kuikui, Chen, Chang, Liu, Jie, Yang, Xiaowei, Chen, Lianming, Xiao, Hongbin, Liu, An
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583968/
https://ncbi.nlm.nih.gov/pubmed/28912717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00586
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