Abnormalities in the Polysomnographic, Adenosine and Metabolic Response to Sleep Deprivation in an Animal Model of Hyperammonemia

Patients with liver cirrhosis can develop hyperammonemia and hepatic encephalopathy (HE), accompanied by pronounced daytime sleepiness. Previous studies with healthy volunteers show that experimental increase in blood ammonium levels increases sleepiness and slows the waking electroencephalogram. As...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Marini, Selena, Santangeli, Olena, Saarelainen, Pirjo, Middleton, Benita, Chowdhury, Namrata, Skene, Debra J., Costa, Rodolfo, Porkka-Heiskanen, Tarja, Montagnese, Sara
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583967/
https://ncbi.nlm.nih.gov/pubmed/28912724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00636
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