HIV-1 tolerates changes in A-count in a small segment of the pol gene

BACKGROUND: The HIV-1 RNA genome has a biased nucleotide composition with a surplus of As. Several hypotheses have been put forward to explain this striking phenomenon, but the A-count of the HIV-1 genome has thus far not been systematically manipulated. The reason for this reservation is the likeli...

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Bibliographic Details
Published in:Retrovirology
Main Authors: Klaver, Bep, van der Velden, Yme, van Hemert, Formijn, van der Kuyl, Antoinette C., Berkhout, Ben
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583962/
https://ncbi.nlm.nih.gov/pubmed/28870251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-017-0367-0
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