Causal relationship between obesity-related traits and TLR4-driven responses at the maternal–fetal interface

AIMS/HYPOTHESIS: Obesity triggers complex inflammatory networks within the innate immune system. During pregnancy, the placenta amplifies the low-grade inflammation through activation of Toll-like receptor 4 (TLR4) signalling pathways. The purpose of this study was to investigate the impact of obesi...

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Pubblicato in:Diabetologia
Autori principali: Yang, Xiaohua, Li, Ming, Haghiac, Maricela, Catalano, Patrick M., O’Tierney-Ginn, Perrie, Mouzon, Sylvie Hauguel-de
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583648/
https://ncbi.nlm.nih.gov/pubmed/27535280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-016-4073-6
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