Effect of large targeted deletions on the mitotic stability of an extra chromosome mediating drug resistance in Leishmania

A mitotically stable linear extra chromosome obtained in a Leishmania donovani strain rendered mycophenolic acid-resistant has been physically mapped. This 290-kb chromosome has an inverted duplicated structure around a central inversion region, and is derived from a conservative amplification event...

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Bibliographic Details

Published in:	Nucleic Acids Res
Main Authors:	Dubessay, Pascal, Ravel, Christophe, Bastien, Patrick, Lignon, Marie-Françoise, Ullman, Buddy, Pagès, Michel, Blaineau, Christine
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 2001
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55836/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11470881/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.15.3231
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