Effect of the fourth nucleotide at the 3′ end of neuraminidase and matrix viral genomic RNA on the pathogenicity of influenza virus A/PR/8/34

Twelve nucleotides located at the 3′ end of viral genomic RNA (vRNA) are conserved among influenza A viruses (IAV) and have a promoter function. Hoffmann's 8-plasmid reverse genetics vector system introduced mutations at position 4, C nucleotide (C4) to U nucleotide (U4), of the 3′ ends of neur...

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Detalles Bibliográficos
Publicado en:J Vet Sci
Main Authors: Lee, Chung-Young, Kwon, Hyuk-Joon, Nguyen, Thanh Trung, Kim, Ilhwan, Jang, Hyung-Kwan, Kim, Jae-Hong
Formato: Artigo
Idioma:Inglês
Publicado: The Korean Society of Veterinary Science 2017
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583418/
https://ncbi.nlm.nih.gov/pubmed/28859270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4142/jvs.2017.18.S1.307
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