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Optimized clade 2.3.2.1c H5N1 recombinant-vaccine strains against highly pathogenic avian influenza

A/Puerto Rico/8/34 (PR8)-derived recombinant viruses have been used for seasonal flu vaccines; however, they are insufficient for vaccines against some human-fatal H5N1 highly pathogenic avian influenza (HPAI) viruses (HPAIV) due to low productivity. Additionally, the polymerase basic 2 (PB2) protei...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Vet Sci
Hauptverfasser: Jang, Jin-Wook, Lee, Chung-Young, Kim, Il-hwan, Choi, Jun-Gu, Lee, Youn-Jeong, Yuk, Seong-Su, Lee, Ji-Ho, Song, Chang-Seon, Kim, Jae-Hong, Kwon, Hyuk-Joon
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Society of Veterinary Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583417/
https://ncbi.nlm.nih.gov/pubmed/28859269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4142/jvs.2017.18.S1.299
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