A novel inducible mutagenesis screen enables to isolate and clone both embryonic and adult zebrafish mutants

Conventional genetic screens for recessive mutants are inadequate for studying biological processes in the adult vertebrate due to embryonic lethality. Here, we report that a novel inducible mutagenesis system enables to study gene function in both embryonic and adult zebrafish. This system yields g...

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Publicado no:Sci Rep
Main Authors: Ma, Zhipeng, Zhu, Peipei, Pang, Meijun, Guo, Liwei, Chang, Nannan, Zheng, Jiyuan, Zhu, Xiaojun, Gao, Ce, Huang, Honghui, Cui, Zongbin, Xiong, Jing-Wei, Peng, Jinrong, Chen, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583359/
https://ncbi.nlm.nih.gov/pubmed/28871129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10968-w
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