An Oligodeoxynucleotide with AAAG Repeats Significantly Attenuates Burn-Induced Systemic Inflammatory Responses by Inhibiting Interferon Regulatory Factor 5 Pathway

Previously, we showed that an oligodeoxynucleotide (ODN) with AAAG repeats (AAAG ODN) rescued mice from fatal acute lung injury (ALI) induced by influenza virus and inhibited production of tumor necrosis factor-α (TNF-α) in the injured lungs. However, its underlying mechanisms remain to be elucidate...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Xiao, Yue, Lu, Wenting, Li, Xin, Zhao, Peiyan, Yao, Yun, Wang, Xiaohong, Wang, Ying, Lin, Zhipeng, Yu, Yongli, Hua, Shucheng, Wang, Liying
Formato: Artigo
Idioma:Inglês
Publicado em: Feinstein Institute for Medical Research 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583065/
https://ncbi.nlm.nih.gov/pubmed/28620671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00243
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