Xanthine oxidase inhibition protects against Western diet-induced aortic stiffness and impaired vasorelaxation in female mice

Consumption of a high-fat, high-fructose diet [Western diet (WD)] promotes vascular stiffness, a critical factor in the development of cardiovascular disease (CVD). Obese and diabetic women exhibit greater arterial stiffness than men, which contributes to the increased incidence of CVD in these wome...

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Vydáno v:Am J Physiol Regul Integr Comp Physiol
Hlavní autoři: Lastra, Guido, Manrique, Camila, Jia, Guanghong, Aroor, Annayya R., Hayden, Melvin R., Barron, Brady J., Niles, Brett, Padilla, Jaume, Sowers, James R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582952/
https://ncbi.nlm.nih.gov/pubmed/28539355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00483.2016
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