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Urine RAS components in mice and people with type 1 diabetes and chronic kidney disease

The pathways implicated in diabetic kidney disease (DKD) are largely derived from animal models. To examine if alterations in renin-angiotensin system (RAS) in humans are concordant with those in rodent models, we measured concentration of angiotensinogen (AOG), cathepsin D (CTSD), angiotensin-conve...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Renal Physiol
Main Authors: Wysocki, Jan, Goodling, Anne, Burgaya, Mar, Whitlock, Kathryn, Ruzinski, John, Batlle, Daniel, Afkarian, Maryam
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582909/
https://ncbi.nlm.nih.gov/pubmed/28468961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00074.2017
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