ATP binding and hydrolysis disrupt the high-affinity interaction between the heme ABC transporter HmuUV and its cognate substrate-binding protein

Using the energy of ATP hydrolysis, ABC transporters catalyze the trans-membrane transport of molecules. In bacteria, these transporters partner with a high-affinity substrate-binding protein (SBP) to import essential micronutrients. ATP binding by Type I ABC transporters (importers of amino acids,...

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Vydáno v:J Biol Chem
Hlavní autoři: Qasem-Abdullah, Hiba, Perach, Michal, Livnat-Levanon, Nurit, Lewinson, Oded
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
Membrane Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582852/
https://ncbi.nlm.nih.gov/pubmed/28710276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.779975
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