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IL-4 up-regulates cyclooxygenase-1 expression in macrophages

Macrophages use various cell-surface receptors to sense their environment and undergo polarized responses. The cytokines, interleukin (IL)-4 and IL-13, released from T-helper type 2 (Th2) cells, drive macrophage polarization toward an alternatively activated phenotype (M2). This phenotype is associa...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Shay, Ashley E., Diwakar, Bastihalli T., Guan, Bo-Jhih, Narayan, Vivek, Urban, Joseph F., Prabhu, K. Sandeep
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582846/
https://ncbi.nlm.nih.gov/pubmed/28684424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.785014
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