The nuclear factor-erythroid 2-related factor/heme oxygenase-1 axis is critical for the inflammatory features of type 2 diabetes–associated osteoarthritis

Epidemiological findings support the hypothesis that type 2 diabetes mellitus (T2DM) is a risk factor for osteoarthritis (OA). Moreover, OA cartilage from patients with T2DM exhibits a greater response to inflammatory stress, but the molecular mechanism is unclear. To investigate whether the antioxi...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Vaamonde-Garcia, Carlos, Courties, Alice, Pigenet, Audrey, Laiguillon, Marie-Charlotte, Sautet, Alain, Houard, Xavier, Kerdine-Römer, Saadia, Meijide, Rosa, Berenbaum, Francis, Sellam, Jérémie
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2017
Sujets:
Molecular Bases of Disease
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582843/
https://ncbi.nlm.nih.gov/pubmed/28684418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.802157
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