Yap promotes hepatocellular carcinoma metastasis and mobilization via governing cofilin/F-actin/lamellipodium axis by regulation of JNK/Bnip3/SERCA/CaMKII pathways

Despite the increasingly important role of Hippo-Yap in hepatocellular carcinoma (HCC) development and progression, little insight is available at the time regarding the specifics interaction of Yap and cancer cells migration. Here, we identified the mechanism by which tumor-intrinsic Yap deletion r...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Shi, Chen, Cai, Yong, Li, Yongheng, Li, Ye, Hu, Nan, Ma, Sai, Hu, Shunying, Zhu, Pingjun, Wang, Weihu, Zhou, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582718/
https://ncbi.nlm.nih.gov/pubmed/28869833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.08.013
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