NADPH oxidase inhibitor, diphenyleneiodonium prevents necroptosis in HK-2 cells

The aim of the present study was to investigate the protective effect of the NADPH oxidase inhibitor, diphenyleneiodonium (DPI) against necroptosis in renal tubular epithelial cells. A necroptosis model of HK-2 cells was established using tumor necrosis factor-α, benzyloxycarbonyl-Val-Ala-Asp-fluoro...

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Veröffentlicht in:Biomed Rep
Hauptverfasser: Dong, Wei, Li, Zhilian, Chen, Yuanhan, Zhang, Li, Ye, Zhiming, Liang, Huaban, Li, Ruizhao, Xu, Lixia, Zhang, Bin, Liu, Shuangxin, Wang, Weidong , Li, Chunling, Luo, Jialun, Shi, Wei, Liang, Xinling
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2017
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582581/
https://ncbi.nlm.nih.gov/pubmed/28894570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2017.948
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