Hirsutine, an Indole Alkaloid of Uncaria rhynchophylla, Inhibits Late Step in Dengue Virus Lifecycle

Dengue virus (DENV) is transmitted to humans by Aedes mosquitoes and is a public health issue worldwide. No antiviral drugs specific for treating dengue infection are currently available. To identify novel DENV inhibitors, we analyzed a library of 95 compounds and 120 extracts derived from crude dru...

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Publicado en:Front Microbiol
Autores principales: Hishiki, Takayuki, Kato, Fumihiro, Tajima, Shigeru, Toume, Kazufumi, Umezaki, Masahito, Takasaki, Tomohiko, Miura, Tomoyuki
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582420/
https://ncbi.nlm.nih.gov/pubmed/28912773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.01674
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