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Clinical development of CAR T cells—challenges and opportunities in translating innovative treatment concepts

Chimeric antigen receptor (CAR) T cell therapy, together with checkpoint inhibition, has been celebrated as a breakthrough technology due to the substantial benefit observed in clinical trials with patients suffering from relapsed or refractory B‐cell malignancies. In this review, we provide a compr...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Hartmann, Jessica, Schüßler‐Lenz, Martina, Bondanza, Attilio, Buchholz, Christian J
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582407/
https://ncbi.nlm.nih.gov/pubmed/28765140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201607485
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