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Re-examination of the intrinsic, dynamic and hydration properties of phosphoramidate DNA
Intrinsic energetic and solvation factors contributing to the unusual structural and biochemical properties of N3′-phosphoramidate DNA analogs have been re-examined using a combination of quantum mechanical and molecular dynamics methods. Evaluation of the impact of the N3′-H substitution was perfor...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2001
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC55823/ https://ncbi.nlm.nih.gov/pubmed/11470880 |
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