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Alterations in fatty acid metabolism and sirtuin signaling characterize early type‐2 diabetic hearts of fructose‐fed rats

Despite the fact that skeletal muscle insulin resistance is the hallmark of type‐2 diabetes mellitus (T2DM), inflexibility in substrate energy metabolism has been observed in other tissues such as liver, adipose tissue, and heart. In the heart, structural and functional changes ultimately lead to di...

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Bibliografiske detaljer
Udgivet i:Physiol Rep
Main Authors: Lou, Phing‐How, Lucchinetti, Eliana, Scott, Katrina Y., Huang, Yiming, Gandhi, Manoj, Hersberger, Martin, Clanachan, Alexander S., Lemieux, Hélène, Zaugg, Michael
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582268/
https://ncbi.nlm.nih.gov/pubmed/28830979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13388
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