Class A CpG Oligonucleotide Priming Rescues Mice from Septic Shock via Activation of Platelet-Activating Factor Acetylhydrolase

Sepsis is a life-threatening, overwhelming immune response to infection with high morbidity and mortality. Inflammatory response and blood clotting are caused by sepsis, which induces serious organ damage and death from shock. As a mechanism of pathogenesis, platelet-activating factor (PAF) induces...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Yamamoto, Yoshinari, Sugimura, Ryu, Watanabe, Takafumi, Shigemori, Suguru, Okajima, Takuma, Nigar, Shireen, Namai, Fu, Sato, Takashi, Ogita, Tasuku, Shimosato, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582170/
https://ncbi.nlm.nih.gov/pubmed/28912777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01049
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