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Apoptosis of pancreatic β-cells in Type 1 diabetes
Type 1 diabetes mellitus (T1DM) results from autoimmune destruction of pancreatic β-cells after an asymptomatic period over years. Insulitis activates antigen presenting cells, which trigger activating CD4+ helper-T cells, releasing chemokines/cytokines. Cytokines activate CD8+ cytotoxic –T cells, w...
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| I publikationen: | Bosn J Basic Med Sci |
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| Huvudupphovsman: | |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5581966/ https://ncbi.nlm.nih.gov/pubmed/28368239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17305/bjbms.2017.1961 |
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