Rab3a-Bound CD63 Is Degraded and Rab3a-Free CD63 Is Incorporated into HIV-1 Particles

CD63, a member of the tetraspanin family, is involved in virion production by human immunodeficiency virus type 1 (HIV-1), but its mechanism is unknown. In this study, we showed that a small GTP-binding protein, Rab3a, interacts with CD63. When Rab3a was exogenously expressed, the amounts of CD63 de...

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Dettagli Bibliografici
Pubblicato in:Front Microbiol
Autori principali: Kubo, Yoshinao, Masumoto, Hiroshi, Izumida, Mai, Kakoki, Katsura, Hayashi, Hideki, Matsuyama, Toshifumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581869/
https://ncbi.nlm.nih.gov/pubmed/28900422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.01653
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