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Development of a Novel Anti-Adhesive Vaccine Against Pseudomonas aeruginosa Targeting the C-terminal Disulfide Loop of the Pilin Protein

Type IV pili (T4P) are major virulence factors of Pseudomonas aeruginosa (P. aeruginosa) that are associated with primary adhesion, biofilm formation and twitching motility. This study focuses on the introduction of a novel biologically active subunit vaccine derived from the disulfide loop (DSL) of...

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Publicat a:Int J Mol Cell Med
Autors principals: Faezi, Sobhan, Bahrmand, Ahmad Reza, Mahdavi, Mehdi, Siadat, Seyed Davar, Nikokar, Iraj, Sardari, Soroush
Format: Artigo
Idioma:Inglês
Publicat: Babol University of Medical Sciences 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581551/
https://ncbi.nlm.nih.gov/pubmed/28890886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22088/acadpub.BUMS.6.2.4
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