Role of zoledronic acid in oncolytic virotherapy: Promotion of antitumor effect and prevention of bone destruction

Osteosarcoma is an aggressive malignant bone tumor that causes bone destruction. Although tumor‐specific replicating oncolytic adenovirus OBP‐301 induces an antitumor effect in an osteosarcoma tumor, it cannot prevent bone destruction. Zoledronic acid (ZOL) is a clinically available agent that inhib...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Yamakawa, Yasuaki, Tazawa, Hiroshi, Hasei, Joe, Osaki, Shuhei, Omori, Toshinori, Sugiu, Kazuhisa, Komatsubara, Tadashi, Uotani, Kouji, Fujiwara, Tomohiro, Yoshida, Aki, Kunisada, Toshiyuki, Urata, Yasuo, Kagawa, Shunsuke, Ozaki, Toshifumi, Fujiwara, Toshiyoshi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581539/
https://ncbi.nlm.nih.gov/pubmed/28685948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13316
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