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Estrogen receptor interaction with estrogen response elements

The estrogen receptor (ER) is a ligand-activated enhancer protein that is a member of the steroid/nuclear receptor superfamily. Two genes encode mammalian ER: ERα and ERβ. ER binds to specific DNA sequences called estrogen response elements (EREs) with high affinity and transactivates gene expressio...

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Bibliographic Details
Main Author: Klinge, Carolyn M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC55815/
https://ncbi.nlm.nih.gov/pubmed/11452016
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