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IGF-II Promotes Stemness of Neural Restricted Precursors
Insulin-like growth factor (IGF)-I and IGF-II regulate brain development and growth through the IGF type 1 receptor (IGF-1R). Less appreciated is that IGF-II, but not IGF-I, activates a splice variant of the insulin receptor (IR) known as IR-A. We hypothesized that IGF-II exerts distinct effects fro...
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| Publicado no: | Stem Cells |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5581406/ https://ncbi.nlm.nih.gov/pubmed/22593020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1095 |
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