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Combined Catalase and ADH Inhibition Ameliorates Ethanol-induced Myocardial Dysfunction Despite Causing Oxidative Stress in Conscious Female Rats

BACKGROUND: Ethanol-evoked oxidative stress, which contributes to myocardial dysfunction in proestrus rats, is mediated by increases in NADPH oxidase activity, malondialdehyde (MDA) and ERK1/2 phosphorylation. Whether these biochemical responses, which are triggered by alcohol-derived acetaldehyde i...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Yao, Fanrong, Abdel-Rahman, Abdel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581241/
https://ncbi.nlm.nih.gov/pubmed/28667748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13442
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