Apatinib inhibits VEGFR-2 and angiogenesis in an in vivo murine model of nasopharyngeal carcinoma

Angiogenesis is initiated by the activation of the vascular epidermal growth factor receptor-2 (VEGFR-2) by the vascular epidermal growth factor (VEGF) ligand. Overexpression of VEGFR-2 increases the growth of nasopharyngeal carcinomas (NPC). Apatinib (YN968D1) is a highly-selective inhibitor of VEG...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Peng, Qiu-Xia, Han, Yun-Wei, Zhang, Yan-Ling, Hu, Jie, Fan, Juan, Fu, Shao-Zhi, Xu, Shan, Wan, Qiang
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581072/
https://ncbi.nlm.nih.gov/pubmed/28881773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17264
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