Excessive matrix metalloprotease-mediated degradation of interstitial tissue (type I collagen) independently predicts short-term survival in an observational study of postmenopausal women diagnosed with cancer

Extensive tissue remodeling mediated by matrix metalloproteases (MMPs) is an important part of cancer. The aim of this study was to investigate whether serum biomarkers reflecting MMP-mediated degradation of type I collagen (C1M), type IV collagen (C4M) and citrullinated vimentin (VICM) were predict...

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Udgivet i:Oncotarget
Main Authors: Willumsen, Nicholas, Bager, Cecilie L., Kehlet, Stephanie N., Dragsbaek, Katrine, Neergaard, Jesper S., Hansen, Henrik B., Bay-Jensen, Anne-Christine, Leeming, Diana J., Lipton, Allan, Christiansen, Claus, Karsdal, Morten
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581046/
https://ncbi.nlm.nih.gov/pubmed/28881747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15275
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