Association of high microvessel α(v)β(3) and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126

Neuroblastoma (NB) is the most common extracranial solid tumor in children. Our previous studies showed that the angiogenic integrin α(v)β(3) was increased in high-risk metastatic (stage 4) NB compared with localized neuroblastomas. Herein, we show that integrin α(v)β(3) was expressed on 68% of micr...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Erdreich-Epstein, Anat, Singh, Alok R., Joshi, Shweta, Vega, Francisco M., Guo, Pinzheng, Xu, Jingying, Groshen, Susan, Ye, Wei, Millard, Melissa, Campan, Mihaela, Morales, Guillermo, Garlich, Joseph R., Laird, Peter W., Seeger, Robert C., Shimada, Hiroyuki, Durden, Donald L.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581022/
https://ncbi.nlm.nih.gov/pubmed/28881723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13386
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