E2/ER β inhibit ISO-induced cardiac cellular hypertrophy by suppressing Ca(2+)-calcineurin signaling

Cardiovascular incidences are markedly higher in men than in pre-menstrual women. However, this advantage in women declines with aging and therefore can be correlated with the sex hormone 17β-Estradiol (E2) which is reported to protect heart cells by acting though estrogen receptors (ERs). In this s...

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Veröffentlicht in:PLoS One
Hauptverfasser: Tsai, Cheng-Yen, Kuo, Wei-Wen, Shibu, Marthandam Asokan, Lin, Yueh-Min, Liu, Chien-Nam, Chen, Yi-Hui, Day, Cecilia-Hsuan, Shen, Chia-Yao, Viswanadha, Vijaya Padma, Huang, Chih-Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580914/
https://ncbi.nlm.nih.gov/pubmed/28863192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184153
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