Comprehensive analysis of amino acid sequence diversity at the F protein cleavage site of Newcastle disease virus in fusogenic activity

Newcastle disease virus (NDV) is a contagious agent of Newcastle disease in avian species and seriously affects the poultry industry. The cleavage site of the viral F protein (Fcs) is a key determinant of membrane fusion and viral virulence. In this study, we investigated the precise effect of varia...

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Veröffentlicht in:PLoS One
Hauptverfasser: Wang, Yanhong, Yu, Wanqi, Huo, Na, Wang, Wenbin, Guo, Yuanyuan, Wei, Qiaolin, Wang, Xinglong, Zhang, Shuxia, Yang, Zengqi, Xiao, Sa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580908/
https://ncbi.nlm.nih.gov/pubmed/28863165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183923
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