CRISPR/Cas9 mediated sequential editing of genes critical for ookinete motility in Plasmodium yoelii

CRISPR/Cas9 has been successfully adapted for gene editing in malaria parasites including Plasmodium falciparum and Plasmodium yoelii. However, the reported methods were limited to editing one gene at a time. In practice, it is often desired to modify multiple genetic loci in a parasite genome. Here...

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Veröffentlicht in:Mol Biochem Parasitol
Hauptverfasser: Zhang, Cui, Gao, Han, Yang, Zhenke, Jiang, Yuanyuan, Li, Zhenkui, Xiao, Bo, Su, Xin-zhuan, Cui, Huiting, Yuan, Jing
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580835/
https://ncbi.nlm.nih.gov/pubmed/28034675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2016.12.010
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