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Multiplexed Gene Editing and Protein Overexpression Using a Tobacco mosaic virus Viral Vector

Development of CRISPR/Cas9 transient gene editing screening tools in plant biology has been hindered by difficulty of delivering high quantities of biologically active single guide RNAs (sgRNAs). Furthermore, it has been largely accepted that in vivo generated sgRNAs need to be devoid of extraneous...

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Bibliographic Details
Published in:Plant Physiol
Main Authors: Cody, Will B., Scholthof, Herman B., Mirkov, T. Erik
Format: Artigo
Language:Inglês
Published: American Society of Plant Biologists 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580747/
https://ncbi.nlm.nih.gov/pubmed/28663331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1104/pp.17.00411
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