DACH1 stimulates shear stress-guided endothelial cell migration and coronary artery growth through the CXCL12–CXCR4 signaling axis

Sufficient blood flow to tissues relies on arterial blood vessels, but the mechanisms regulating their development are poorly understood. Many arteries, including coronary arteries of the heart, form through remodeling of an immature vascular plexus in a process triggered and shaped by blood flow. H...

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Veröffentlicht in:Genes Dev
Hauptverfasser: Chang, Andrew H., Raftrey, Brian C., D'Amato, Gaetano, Surya, Vinay N., Poduri, Aruna, Chen, Heidi I., Goldstone, Andrew B., Woo, Joseph, Fuller, Gerald G., Dunn, Alexander R., Red-Horse, Kristy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580653/
https://ncbi.nlm.nih.gov/pubmed/28779009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.301549.117
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