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Androgen Signaling in Prostate Cancer
The androgen-signaling axis plays a pivotal role in the pathogenesis of prostate cancer. Since the landmark discovery by Huggins and Hodges, gonadal depletion of androgens has remained a mainstay of therapy for advanced disease. However, progression to castration-resistant prostate cancer (CRPC) typ...
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| Veröffentlicht in: | Cold Spring Harb Perspect Med |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5580512/ https://ncbi.nlm.nih.gov/pubmed/28389515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a030452 |
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