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Androgen Signaling in Prostate Cancer

The androgen-signaling axis plays a pivotal role in the pathogenesis of prostate cancer. Since the landmark discovery by Huggins and Hodges, gonadal depletion of androgens has remained a mainstay of therapy for advanced disease. However, progression to castration-resistant prostate cancer (CRPC) typ...

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Foilsithe in:Cold Spring Harb Perspect Med
Main Authors: Dai, Charles, Heemers, Hannelore, Sharifi, Nima
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580512/
https://ncbi.nlm.nih.gov/pubmed/28389515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a030452
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