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Homeostasis Back and Forth: An Ecoevolutionary Perspective of Cancer

The role of genetic mutations in cancer is indisputable: They are a key source of tumor heterogeneity and drive its evolution to malignancy. But, the success of these new mutant cells relies on their ability to disrupt the homeostasis that characterizes healthy tissues. Mutated clones unable to brea...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: Basanta, David, Anderson, Alexander R.A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580509/
https://ncbi.nlm.nih.gov/pubmed/28289244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a028332
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