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Targeting PAR1: Now what?
Protease-activated receptors (PARs) are a ubiquitously expressed class of GPCRs that enable cells to respond to proteases in the extracellular environment in a nuanced and dynamic manner. PAR1 is the archetypal family member and has been the object of large-scale drug development programs since the...
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| Publicado no: | Trends Pharmacol Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5580498/ https://ncbi.nlm.nih.gov/pubmed/28558960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2017.05.001 |
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