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No Systemic Exposure of Trans Tympanic Heparin Binding Epidermal Growth Factor Like Growth Factor

CONTEXT: Heparin binding epidermal growth factor like growth factor (HB-EGF) is an emerging therapeutic for the regeneration of the tympanic membrane. OBJECTIVE: Our aim was to determine whether the doses of HB-EGF delivered in a sustained release hydrogel into a middle ear mouse model, would be mea...

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Detalhes bibliográficos
Publicado no:Drug Chem Toxicol
Main Authors: Santa Maria, Peter Luke, Kim, Sungwoo, Yang, Yunzhi Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580497/
https://ncbi.nlm.nih.gov/pubmed/26887920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/01480545.2016.1143482
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