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A streamlined method for analysing genome-wide DNA methylation patterns from low amounts of FFPE DNA
BACKGROUND: Formalin fixed paraffin embedded (FFPE) tumor samples are a major source of DNA from patients in cancer research. However, FFPE is a challenging material to work with due to macromolecular fragmentation and nucleic acid crosslinking. FFPE tissue particularly possesses challenges for meth...
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| Gepubliceerd in: | BMC Med Genomics |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5580311/ https://ncbi.nlm.nih.gov/pubmed/28859641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-017-0290-1 |
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