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Leucine aminopeptidase may contribute to the intrinsic resistance of cancer cells toward cisplatin as revealed by an ultrasensitive fluorescent probe

Cisplatin, a typical anticancer drug, is often used to treat different cancers, and leucine aminopeptidase (LAP) is known to be widely distributed in organisms from bacteria to humans, including various cancer cells. However, cancer cells display different intrinsic or acquired resistance toward cis...

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Publicado en:Chem Sci
Main Authors: Gong, Qiuyu, Shi, Wen, Li, Lihong, Ma, Huimin
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580032/
https://ncbi.nlm.nih.gov/pubmed/28966770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03600c
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