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Inhibitory Effect of Lycopene on Amyloid-β-Induced Apoptosis in Neuronal Cells

Alzheimer′s disease (AD) is a fatal neurodegenerative disease. Brain amyloid-β deposition is a crucial feature of AD, causing neuronal cell death by inducing oxidative damage. Reactive oxygen species (ROS) activate NF-κB, which induces expression of Nucling. Nucling is a pro-apoptotic factor recruit...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Hwang, Sinwoo, Lim, Joo Weon, Kim, Hyeyoung
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579676/
https://ncbi.nlm.nih.gov/pubmed/28813012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu9080883
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