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Analysis of mutant allele fractions in driver genes in colorectal cancer – biological and clinical insights
Sequencing of tumors is now routine and guides personalized cancer therapy. Mutant allele fractions (MAFs, or the ‘mutation dose’) of a driver gene may reveal the genomic structure of tumors and influence response to targeted therapies. We performed a comprehensive analysis of MAFs of driver alterat...
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| Vydáno v: | Mol Oncol |
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| Hlavní autoři: | , , , , , , , , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley and Sons Inc.
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5579330/ https://ncbi.nlm.nih.gov/pubmed/28618197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12099 |
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