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A CDC42-centered signaling unit is a dominant positive regulator of endothelial integrity

Endothelial barrier function is carefully controlled to protect tissues from edema and damage inflicted by extravasated leukocytes. RhoGTPases, in conjunction with myriad regulatory proteins, exert both positive and negative effects on the endothelial barrier integrity. Precise knowledge about the r...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Amado-Azevedo, J., Reinhard, N. R., van Bezu, J., de Menezes, R. X., van Beusechem, V. W., van Nieuw Amerongen, G. P., van Hinsbergh, V. W. M., Hordijk, P. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579287/
https://ncbi.nlm.nih.gov/pubmed/28860633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10392-0
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